L-DOPA Association with Reduced Detection of New-Onset GA
Source: Eye and Vision, 2024 Background Geographic atrophy (GA) is a significant cause of vision loss in patients with age-related macular degeneration (AMD). Current treatments are limited to anti-complement drugs, which have limited efficacy to delay progression with significant risk of complications. Levodopa (L-DOPA) is a byproduct of melanin synthesis that is associated with reduced…
Read MoreRole of L-DOPA in Prevention of GA
Source: Eye and Vision, 2024 Background Geographic atrophy (GA) is a significant cause of vision loss in patients with age-related macular degeneration (AMD). Current treatments are limited to anti-complement drugs, which have limited efficacy to delay progression with significant risk of complications. Levodopa (L-DOPA) is a byproduct of melanin synthesis that is associated with reduced…
Read MoreWarnings Before Taking MaculaPM™
As with any supplement, if you are pregnant, nursing, taking medications, have a medical condition or have difficulty swallowing, consult your doctor before use. Warning Language for L-Dopa: If you are taking medications (especially methyldopa, tricyclic antidepressants, or MAOIs) or have a medical condition including a history of melanoma, diabetes, peptic ulcer, liver disease, psychiatric…
Read MoreDifferent Therapeutic Approaches for AMD
Source: Department of Drug Sciences, Section of Pharmacology, University of Pavia Abstract: Age-related macular degeneration (AMD) is the most common cause of irreversible loss of central vision in elderly subjects, affecting men and women equally. It is a degenerative pathology that causes progressive damage to the macula, the central and most vital part of the…
Read MoreAREDS / AREDS2 Clinical Trials
Age-Related Eye Disease Studies (AREDS/AREDS2): major findings Source: NEI The NEI conducted the Age-Related Eye Disease Study (AREDS) and the follow-on AREDS2 to study cataract and age-related macular degeneration (AMD). Study researchers tested whether taking nutritional supplements could prevent or slow these diseases. The formulations tested in the trials are now sold as the AREDS…
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