L-DOPA Association with Reduced Detection of New-Onset GA

Source: Eye and Vision, 2024 Background Geographic atrophy (GA) is a significant cause of vision loss in patients with age-related macular degeneration (AMD). Current treatments are limited to anti-complement drugs, which have limited efficacy to delay progression with significant risk of complications. Levodopa (L-DOPA) is a byproduct of melanin synthesis that is associated with reduced…

Read More

Additional Patents Licensed for Use

(a) United States Patent Number U.S. 11,969,401 entitled •compositions and Methods for Treating or Limiting Development of Age-Related Macular Degeneration· issued on April 30, 2024 {ARIZONA Ref No. UA19-094); and (b) United States Patent Number U.S. 9,173,862 entitled “Methods and Compositions for Treating and Identifying Compounds to Treat Age-Related Macular Degeneration” issued on November 3,…

Read More

Role of L-DOPA in Prevention of GA

Source: Eye and Vision, 2024 Background Geographic atrophy (GA) is a significant cause of vision loss in patients with age-related macular degeneration (AMD). Current treatments are limited to anti-complement drugs, which have limited efficacy to delay progression with significant risk of complications. Levodopa (L-DOPA) is a byproduct of melanin synthesis that is associated with reduced…

Read More

Warnings Before Taking MaculaPM™

As with any supplement, if you are pregnant, nursing, taking medications, have a medical condition or have difficulty swallowing, consult your doctor before use. Warning Language for L-Dopa: If you are taking medications (especially methyldopa, tricyclic antidepressants, or MAOIs) or have a medical condition including a history of melanoma, diabetes, peptic ulcer, liver disease, psychiatric…

Read More

Different Therapeutic Approaches for AMD

Source: Department of Drug Sciences, Section of Pharmacology, University of Pavia Abstract: Age-related macular degeneration (AMD) is the most common cause of irreversible loss of central vision in elderly subjects, affecting men and women equally. It is a degenerative pathology that causes progressive damage to the macula, the central and most vital part of the…

Read More